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Berann Biotech
  • Home
  • About
  • Our Science
  • R&D Portofolio
  • Partnering
  • Contact

Our Signal‑First™ Platform

We map skin‑relevant signaling nodes and design topical ligands/peptides that gently bias those nodes toward resilience.


Focus Areas:

  1. Barrier Intelligence – Upregulate lipid handling and tight‑junction harmony; 
  2. Calm & Balance – Tame inflammaging signals
  3. Matrix Renewal – Encourage a youthful ECM balance by supporting pro‑collagen expression and reining in excess MMP activity; improve dermal density aesthetics.
  4. Dynamics of hydration, signaling, and cell‑matrix dialog.
  5. UV/Urban Stress Response – Antioxidant‑signaling support and mitochondrial comfort to reduce the look of fatigue and uneven tone.


How we build it

  • In‑silico design (molecular motifs, docking heuristics for topical targets)
  • Peptide synthesis 
  • Delivery engineering (ethosomes/liposomes/film‑forming gels)
  • Bench to user (3D skin models → dermatologist‑supervised HRIPT/user studies)


Regulatory stance: We design cosmetic technologies under EU Reg. 1223/2009 claim‑substantiation principles and dermatological test standards.


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